Serum selenium level and heart disease

Dietary selenium intakes in the Nordic countries are generally quite low.  In Finland, the situation is different because, there, the government implemented a policy of selenium fertilization of the soil.  As a result, Finns have a much higher selenium intake than their Nordic neighbors. Unfortunately, there is not enough selenium available for every selenium-poor region in the world to use soil fertilization as a solution. Supplementation is the more efficient option.

Daily supplementation for four years with a high-selenium yeast tablet and two Coenzyme Q10 capsules reduced the risk of death from heart disease in elderly men and women aged 70-80 years at the time of enrollment into the KiSel-10 randomized controlled trial.  The effective dosages were 200 micrograms of selenium and 200 milligrams of Coenzyme Q10 (100 milligrams twice a day) [Alehagen 2013].

The daily supplementation also maintained good heart function as documented on echocardiograms and reduced the concentrations of bio-markers for oxidative damage and low-grade inflammation.  Best of all, the beneficial health effects of the selenium and Coenzyme Q10 persisted for up to ten years after the four-year supplementation [Alehagen 2015].

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