The Su.Vi.Max. study — SUpplementation en VItamines et Minéraux AntioXydants — was a big randomized, double-blind, placebo-controlled study carried out with typical French efficiency. Even though I have written the name of the study in French, there are so many English cognates that I am sure you can read the full name of the study.
The study was designed to test the health benefits of daily supplementation with a number of vitamins and minerals at nutritional dosages (roughly, one to three times the daily recommended dietary intakes) [Hercberg 1998]:
- selenium, 100 micrograms
- vitamin C, 120 mg
- vitamin E, 30 mg
- beta-carotene, 6 mg
- zinc, 20 mg
In particular, the French researchers wanted to see the effect of the daily supplementation over a long period, approximately 7.5 years, from 1994 to 2002, on the prevention of cancer and cardiovascular disease, both of which have been linked to oxidative stress and oxidative damage and might, therefore, be affected by supplementation with antioxidants.