Selenium and Type 2 Diabetes

Selenium supplementation and the possible risk of developing type 2 diabetes, what do we know? This is a complex issue. Many different biological, hormonal, and environmental factors have an effect on the relationship.

Diabetes
Observational evidence points to relevant sex differences in the selenium-diabetes interrelationship. There may be potential harmful effects in men living in selenium-rich areas and in men with high habitual selenium intake. Research shows potential benefits of selenium on diabetes risk in women selenium-deficient areas or in women with low selenium intake.

In a 2024 review, Demircan and a selenium research team headed by Prof Lutz Schomburg, Charité Berlin, investigated the current evidence for a relationship between selenium and type 2 diabetes. Recent evidence points to selenium intake and serum selenium status as relevant factors in the study of type 2 diabetes complications and prognosis.

Two studies based on data from the National Health and Nutrition Examination Survey (NHANES) in the United States have identified selenium intake and serum selenium status, respectively, as associated with the improved survival of type 2 diabetes patients [Demircan 2024]. read more

Selenium and Vitamin D for Thyroid Health

Supplementation with selenium and vitamin D can improve the prognosis of type 2 diabetes mellitus and Hashimoto’s thyroiditis. Adding a daily dose of selenium and vitamin D to conventional diabetes medication can give significant health benefits [Yu 2024].

Selenium and Vitamin D for Type 2 Diabetes and Thyroid Disorder
A Chinese study suggests that combining conventional diabetes medicine with selenium and vitamin D supplements  reduces the levels of TSH and TPOAb and blood glucose and blood lipids in patients with concomitant type 2 diabetes and Hashimoto’s thyroiditis.

Researchers at Hunan University of Chinese Medicine, Hunan Province, China, recommend 100-200 mcg/day of selenium and 100 mcg/day of vitamin D for three to six months for patients with Hashimoto’s thyroiditis and especially for Hashimoto’s thyroiditis patients with concomitant type 2 diabetes [Yu 2024].

A 2024 study by Feng et al has shown that adding 200 mcg of selenium daily and 100 mcg of vitamin D to standard anti-diabetic drugs significantly improved thyroid function, thyroid antibodies, blood glucose, and blood lipids in type 2 diabetes patients who were also diagnosed with Hashimoto’s thyroiditis. read more