{"id":1225,"date":"2019-02-26T18:31:43","date_gmt":"2019-02-26T18:31:43","guid":{"rendered":"http:\/\/seleniumfacts.com\/?p=1225"},"modified":"2019-03-04T10:47:22","modified_gmt":"2019-03-04T10:47:22","slug":"selenium-supplementation-insulin-resistance-clinical-study","status":"publish","type":"post","link":"https:\/\/seleniumfacts.com\/index.php\/selenium-supplementation-insulin-resistance-clinical-study","title":{"rendered":"Selenium supplementation and insulin resistance: a clinical study"},"content":{"rendered":"
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The latest clinical evidence shows that selenium supplementation of older adults with 200 micrograms of a high-selenium yeast preparation for up to three years does not adversely affect pancreatic beta-cell function or insulin sensitivity. <\/strong><\/figcaption><\/figure>\n

Results from a clinical trial comparing 200 micrograms of selenium supplementation with placebo supplementation show no effect of the selenium supplementation on measures of insulin secretion and insulin action [Jacobs].\u00a0<\/strong><\/p>\n

These results can be regarded as important evidence that selenium supplementation for up to three years in older individuals has no diabetes causing effects in humans<\/a> [Jacobs].<\/strong><\/p>\n

The researchers who conducted the selenium and insulin resistance study concluded that the results of the study do not show a causal role for selenium in the development of insulin resistance or in the development of type-2 diabetes [Jacobs].<\/strong><\/p>\n

Research design of the selenium and insulin resistance study<\/h3>\n

Background: In 2016, researchers at the Arizona Cancer Center in Tucson reported on the results of the Selenium Trial<\/a> [Thompson].<\/p>\n

In that study, researchers enrolled men and women aged 40 to 80 years from endoscopy clinics in Arizona, Colorado, New York, and Texas. They tested the effect of a high-selenium yeast supplement on the prevention of colorectal adenomas and on the risk of associated Type 2 diabetes [Thompson].<\/p>\n

For the present study, a study of possible effects of selenium supplementation on the risk of developing diabetes, the researchers selected 400 participants from the bigger Selenium Trial.\u00a0 The 400 participants<\/em><\/strong> were randomly assigned to a selenium supplementation group (n = 205) or to a placebo group (n = 195).<\/p>\n

There were approximately 1\/3 women and 2\/3 men among the 400 participants.<\/p>\n

The average age of the participants was 63 years<\/em><\/strong> plus\/minus 8.9 years.<\/strong><\/p>\n

Outcome assessments in the selenium and insulin resistance study<\/h3>\n

The researchers assessed two primary endpoints:<\/p>\n