{"id":3276,"date":"2024-01-15T13:26:08","date_gmt":"2024-01-15T13:26:08","guid":{"rendered":"https:\/\/seleniumfacts.com\/?p=3276"},"modified":"2023-11-22T08:59:05","modified_gmt":"2023-11-22T08:59:05","slug":"selenium-intakes-and-health-outcomes","status":"publish","type":"post","link":"https:\/\/seleniumfacts.com\/index.php\/selenium-intakes-and-health-outcomes","title":{"rendered":"Selenium Intakes and Health Outcomes"},"content":{"rendered":"

Selenium and good health. How much do we need? How do we get it? Generally speaking, our family and friends do not know just how important selenium is to good health. Our bodies cannot synthesize selenium. We are dependent upon food for an adequate daily intake of this essential trace element.<\/strong><\/p>\n

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Depending upon where we live, the selenium content of our food may be too low. Wang et al [2023] estimate that approximately one billion people worldwide lack sufficient selenium in their diet.<\/strong><\/figcaption><\/figure>In many regions of the world, the soil and the foodstuffs have a poor selenium content. Accordingly, the daily intake of selenium varies considerably. Many people have an inadequate supply and thus risk poor health outcomes as a result. For example, in much of Europe, the UK, and the Middle East, there are widespread reports of suboptimal selenium status. Supplementation is necessary in selenium-poor regions [Stoffaneller & Morse 2015].<\/strong><\/p>\n
Selenium Intake and Selenoprotein Synthesis<\/h5>\n

We need an adequate intake of selenium in order to synthesize the 25 known selenoproteins that have diverse tissue distributions and biological functions in humans. The selenoproteins incorporate the selenium as a component of the 21st amino acid, selenocysteine [Schomburg & Schweizer 2009].<\/p>\n

Many selenoproteins function as enzymes and factors that regulate redox reactions and immune responses. The glutathione peroxidases, thioredoxin reductases, iodothyronine deiodinases, and the primary selenium transporter in the blood circulation, Selenoprotein P, are representative selenoproteins [Wang 2023].<\/p>\n

Selenium Intake and Selenium Supplementation<\/h5>\n

Adequate selenium intake, as compared with sub-optimal selenium intake<\/a>, has been associated with a reduced risk of the following conditions [Wang 2023]:<\/p>\n