{"id":872,"date":"2018-02-02T14:46:48","date_gmt":"2018-02-02T14:46:48","guid":{"rendered":"http:\/\/seleniumfacts.com\/?p=872"},"modified":"2018-02-07T15:25:14","modified_gmt":"2018-02-07T15:25:14","slug":"documented-properties-high-selenium-yeast-preparation","status":"publish","type":"post","link":"https:\/\/seleniumfacts.com\/index.php\/documented-properties-high-selenium-yeast-preparation","title":{"rendered":"Properties of a high-selenium yeast preparation"},"content":{"rendered":"<figure id=\"attachment_888\" aria-describedby=\"caption-attachment-888\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-888 size-medium\" src=\"http:\/\/seleniumfacts.com\/wp-content\/uploads\/2018\/02\/Se-element-300x80.png\" alt=\"\" width=\"300\" height=\"80\" srcset=\"https:\/\/seleniumfacts.com\/wp-content\/uploads\/2018\/02\/Se-element-300x80.png 300w, https:\/\/seleniumfacts.com\/wp-content\/uploads\/2018\/02\/Se-element.png 641w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-888\" class=\"wp-caption-text\"><strong>The element selenium is seldom found alone and unbound. In the body, it forms a part of the amino acids selenomethionine and selenocysteine and functions as a component of some 25 selenoproteins. The high-selenium yeast used in nutritional supplements is produced by enriching <em>Saccharomyces cerevisiae<\/em> yeast (also known as baker\u2019s yeast or brewer\u2019s yeast) with selenium. As the yeast grows, it absorbs the selenium. The result is an organic high-selenium yeast that has a relatively good absorption and bio-availability. It provides several species of selenium that are necessary for many cellular functions in the body. The yeast in the high-selenium yeast tablets is dead. It cannot cause yeast infections.<\/strong><\/figcaption><\/figure>\n<p><strong>The evidence from clinical studies shows that high-selenium yeast preparations give the best health outcomes [Alehagen; Blot; Clark; Yu].<\/strong><\/p>\n<p><strong>Today, I want to look at the documented properties of the high-selenium yeast preparation that was developed for use in the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18062829\" target=\"_blank\" rel=\"noopener noreferrer\">PRECISE studies<\/a>.\u00a0 PRECISE is the acronym for PREvention of Cancer by Intervention with SElenium.\u00a0 The PRECISE studies were designed to test the effectiveness of selenium supplementation at preventing cancer.<\/strong><\/p>\n<p><strong>The preparation is also the high-selenium yeast preparation used in the <a href=\"http:\/\/healthandscience.eu\/index.php?option=com_content&amp;view=article&amp;id=864:supplementation-with-q10-and-selenium-halves-your-cardiovascular-risk-for-numerous-years-us&amp;catid=20&amp;Itemid=374&amp;lang=us\" target=\"_blank\" rel=\"noopener noreferrer\">KiSel-10 study <\/a>of combined selenium and Coenzyme Q10 supplementation of healthy elderly citizens to protect against heart disease.\u00a0 Professor Urban Alehagen and the <a href=\"http:\/\/healthandscience.eu\/index.php?option=com_content&amp;view=article&amp;id=445:swedish-scientists-behind-amazing-discovery&amp;catid=20&amp;Itemid=198&amp;lang=en\" target=\"_blank\" rel=\"noopener noreferrer\">researchers at Link\u00f6ping University<\/a> in Sweden have written about the special interrelationship between selenium and Coenzyme Q10: our cells need adequate selenium status to obtain optimal concentrations of Coenzyme Q10, and our cells need adequate Coenzyme Q10 status to realize optimal selenoprotein function [Alehagen].<\/strong><\/p>\n<p>A high-selenium yeast preparation must have scientific documentation for the following properties:<\/p>\n<ul>\n<li><strong>stability<\/strong><\/li>\n<li><strong>absorption and bio-availability<\/strong><\/li>\n<li><strong>efficacy<\/strong><\/li>\n<li><strong>safety<\/strong><\/li>\n<\/ul>\n<h3>Stability<\/h3>\n<p>The effective high-selenium yeast preparation contains approximately 60% natural (not synthetic) l-selenomethionine and as many as 30 other species of selenium including <em>gamma-glutamyl<\/em>-Se-methylselenocysteine.\u00a0 Methylselenocysteine is thought to be an important component of an effective high-selenium yeast preparation.\u00a0 <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15084104\" target=\"_blank\" rel=\"noopener noreferrer\">Speciation studies<\/a> have shown that high-selenium yeast preparation contains less than one percent inorganic selenium [Larsen].<\/p>\n<p>What are we talking about here?\u00a0 There are different forms of selenium \u2013 both inorganic and organic &#8212; that a manufacturer of a selenium supplement can use.\u00a0 The results from randomized controlled studies show that organic high-selenium yeast preparations confer more health benefits than inorganic selenium preparations do [Alehagen; Clark; Blot; Yu].<\/p>\n<p>In addition, high-selenium yeast preparations containing organic l-selenomethionine have been associated with better health outcomes than selenium preparations with a synthetic l-selenomethionine have.\u00a0 Compare, for example, the results of the Nutritional Prevention of Cancer study with the results of the SELECT study [Clark; Lippman].<\/p>\n<p><strong><em>The important thing for us consumers is that we can count on getting a stable, standardized pharmaceutical-grade selenium preparation that has the same proportions of species of selenium in batch after batch.<\/em><\/strong><\/p>\n<h3>Absorption and bio-availability<\/h3>\n<p>In the same way, it is important to us to purchase a high-selenium yeast tablet that has a high absorbability, e.g. somewhere between 80% and 90%, consistently.<\/p>\n<p>Depending on the region we live in, we may need a daily supplement of 50 micrograms, 100 micrograms, or 200 micrograms.\u00a0 It is possible to have our plasma or serum selenium concentrations tested.\u00a0 Scientific interpretation of clinical study outcomes suggests that the effective plasma selenium range for <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22648711\" target=\"_blank\" rel=\"noopener noreferrer\">cancer prevention<\/a> is between 120 micrograms per liter and 170 micrograms per liter [Hurst 2012].<\/p>\n<p>The manufacturer of an effective high-selenium yeast preparation has documented evidence that a daily supplement of 100 micrograms will increase an individual\u2019s plasma selenium concentration by more than 50% after a few months of steady supplementation, all depending, of course, upon the baseline plasma selenium status of the individual [Larsen].<\/p>\n<h3>Efficacy of high-selenium yeast in disease prevention<\/h3>\n<p>Arguably, the two biggest health benefits of selenium supplementation \u2013 upon raising selenium status to effective levels \u2013 are prevention of cancer and enhancement of thyroid function.<\/p>\n<p>I have posted several articles about selenium and cancer risk on this web-site.\u00a0 I will be summarizing the bio-medical literature about selenium and thyroid function in a future article.<\/p>\n<p>In the remainder of this article, I would like to review some other health outcomes associated with a pharmaceutical-grade high-selenium yeast preparation.<\/p>\n<h4>High-selenium yeast and pregnancy<\/h4>\n<p><strong>Reduced oxidative stress:<\/strong> The levels of bio-markers of oxidative stress increase significantly during pregnancy.\u00a0 Understandably.\u00a0 Supplementation of first trimester pregnant women with 100 micrograms per day for six months kept the levels of <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20629489\" target=\"_blank\" rel=\"noopener noreferrer\">pregnancy-related oxidative stress bio-markers<\/a> unchanged.\u00a0 In the placebo group, the same pregnancy-related oxidative stress bio-markers increased by 32%.\u00a0 The selenium supplementation had a protective effect [Tara 2010].<\/p>\n<p><strong>Less post-partum depression:<\/strong> Supplementing first trimester pregnant women with 100 micrograms per day until delivery was associated with significantly reduced incidence of <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20528216\" target=\"_blank\" rel=\"noopener noreferrer\">post-partum depression<\/a> [Mokhber 2011].<\/p>\n<p><strong>Reduced risk of pre-eclampsia:<\/strong> Daily supplementation of pregnant women with 60 micrograms of high-selenium yeast from week 12-14 until delivery was associated with lower concentrations of SFlt-1 proteins, which are bio-markers for the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24708917\" target=\"_blank\" rel=\"noopener noreferrer\">risk of pre-eclampsia<\/a>.\u00a0 The supplementation with 60 micrograms daily was also associated with higher maternal levels of Selenoprotein P, which are normally reduced during pregnancy because of the transfer of selenium to the fetus [Rayman 2014].<\/p>\n<p><strong>Reduced risk of pre-labor rupture of membranes:<\/strong> The incidence of <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20121500\" target=\"_blank\" rel=\"noopener noreferrer\">pre-labor rupture of membranes<\/a> in first-time-pregnant women who were supplemented with 100 micrograms of high-selenium yeast daily was significantly lower than the incidence in the placebo group [Tara 2010].<\/p>\n<h4>High-selenium yeast and mercury excretion<\/h4>\n<p>Daily supplementation with 100 micrograms of high-selenium yeast for 90 days was associated with sharply increased <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23033886\" target=\"_blank\" rel=\"noopener noreferrer\">mercury excretion<\/a> in study participants with long-term exposure to mercury [Li 2012].<\/p>\n<h4>High-selenium yeast and improved immune system function<\/h4>\n<p>Researchers supplemented study participants with 0, 50, 100, or 200 micrograms of high-selenium yeast daily for 12 weeks.\u00a0 They administered an influenza vaccine to the study participants.\u00a0 There was a dose-dependent up-regulation of the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3061857\/\" target=\"_blank\" rel=\"noopener noreferrer\">immune system response<\/a> to the vaccine [Goldson 2011].<\/p>\n<h4>High-selenium yeast and cholesterol levels<\/h4>\n<p>A study of elderly British study participants supplemented with 0, 100, 200, or 300 micrograms of high-selenium yeast for six months showed modestly beneficial outcomes in the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/21576533\" target=\"_blank\" rel=\"noopener noreferrer\">total cholesterol-HDL good cholesterol ratios<\/a>.\u00a0 The ratios of total cholesterol to good cholesterol decreased in response to increasing high-selenium yeast dosages [Rayman 2011].\u00a0 Put another way, good cholesterol was a higher percentage of the total cholesterol in the study participants taking higher dosages of high-selenium yeast.<\/p>\n<p>A study of elderly Danish study participants supplemented with 0, 100, 200, or 300 micrograms of high-selenium yeast for five years showed the same trend towards improved cholesterol ratios with increasing dosages of high-selenium yeast [Cold 2015]. These results stopped short of statistical significance; however, the improvements in good cholesterol may have clinical significance.<\/p>\n<h4>High-selenium yeast and heart disease<\/h4>\n<p>In the <a href=\"http:\/\/healthandscience.eu\/index.php?option=com_content&amp;view=article&amp;id=445:swedish-scientists-behind-amazing-discovery&amp;catid=20&amp;Itemid=198&amp;lang=en\" target=\"_blank\" rel=\"noopener noreferrer\">KiSel-10 study<\/a>,\u00a0 combined supplementation with high-selenium yeast and Coenzyme Q10 was associated with significantly reduced risk of death from heart disease [Alehagen].<\/p>\n<h4>High-selenium yeast and chronic kidney disease<\/h4>\n<p>At baseline, patients with<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/m\/pubmed\/20661660\/\" target=\"_blank\" rel=\"noopener noreferrer\"> chronic kidney disease<\/a> had DNA damage in white blood cells three times the level of healthy individuals.\u00a0 Daily supplementation of the chronic kidney disease patients with 200 micrograms for three months was associated with a significant decrease in DNA damage in white blood cells, down to a level that was 16% lower than the levels of DNA damage in healthy individuals [Zachara 2011].<\/p>\n<h3>Safety of high-selenium yeast<\/h3>\n<h4>No serious adverse effects:<\/h4>\n<p>A review of the results of 47 studies with a pharmaceutical-grade high-selenium yeast preparation has shown no reports of serious adverse effects and no alterations in the study participants\u2019 toxicity parameters [Sindberg 2016].<\/p>\n<h4>No muscle tissue build-up:<\/h4>\n<p>Long-term supplementation for several years with dosages ranging from 62.5 to 262.5 micrograms resulted in a <strong><em>selenium steady state in muscle tissue<\/em><\/strong>.\u00a0 There was <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20413067\" target=\"_blank\" rel=\"noopener noreferrer\">no continuous build-up <\/a>and no danger of toxic build-up in muscle tissue.\u00a0 Moreover, there was a significant positive correlation between muscle tissue selenium levels and selenium concentrations in plasma, whole blood, red blood cells, head hair, and toe nails [Behne 2010].<\/p>\n<h4>High-selenium yeast and diabetes:<\/h4>\n<p>Daily supplementation of elderly study participants with low selenium status with 100, 200, and 300 micrograms for six months had <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23028897\" target=\"_blank\" rel=\"noopener noreferrer\">no effect on adiponectin levels<\/a> thus reassuring researchers that selenium supplementation did not show a diabetic effect in a sample of elderly individuals with relatively low selenium status [Rayman 2012].<\/p>\n<h4>High-selenium yeast and pregnancy:<\/h4>\n<p>Daily supplementation with 100 micrograms of high-selenium yeast from the first trimester until delivery seems to be safe in pregnancy and is quite possibly much needed [Tara 2010; Mokhber 2011; Rayman 2014].<\/p>\n<h3>Conclusion<\/h3>\n<p>In the body, the selenium from supplements is incorporated into selenoproteins that have a number of beneficial health effects:<\/p>\n<ul>\n<li>antioxidant effects<\/li>\n<li>anti-inflammatory effects<\/li>\n<li>anti-viral effects<\/li>\n<\/ul>\n<p>It is important to choose a <a href=\"https:\/\/www.pharmanord.com\/us-products\/selenoprecise\" target=\"_blank\" rel=\"noopener noreferrer\">high-selenium yeast preparation<\/a> with documented stability, absorption, efficacy, and safety.<\/p>\n<h3>Sources<\/h3>\n<p>Alehagen, U., Johansson, P., Bj\u00f6rnstedt, M., Ros\u00e9n, A., &amp; Dahlstr\u00f6m, U. (2013). Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and Coenzyme Q10 supplementation: a 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citizens. International Journal of Cardiology, 167(5), 1860-1866. doi:10.1016\/j.ijcard.2012.04.156<\/p>\n<p>Behne, D., Alber, D., &amp; Kyriakopoulos, A. (2010). Long-term selenium supplementation of humans: selenium status and relationships between selenium concentrations in skeletal muscle and indicator materials. Journal of Trace Elements in Medicine and Biology, 24(2), 99-105. doi:10.1016\/j.jtemb.2009.12.001<\/p>\n<p>Blot, W. J., Li, J. Y., Taylor, P. R., Guo, W., Dawsey, S., Wang, G. Q., &amp; Li, B. (1993). Nutrition intervention trials in Linxian, China: supplementation with specific vitamin\/mineral combinations, cancer incidence, and disease-specific mortality in the general population. Journal of The National Cancer Institute, 85(18), 1483- 1492.<\/p>\n<p>Clark, L. C., Combs, G. J., Turnbull, B. W., Slate, E. H., Chalker, D. K., Chow, J., &amp; \u2026 Taylor, J. R. (1996). Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group. JAMA, 276(24), 1957-1963.<\/p>\n<p>Cold, S., Winther, K. H., Pastor-Barriuso, R., &amp; Rayman, M. P. (2015). Randomised controlled trial of the effect of long-term selenium supplementation on plasma cholesterol.\u00a0 British Journal of Nutrition, 114(11): 1807-18.<\/p>\n<p>Goldson, A. J., Fairweather-Tait, S. J., Armah, C. N., Bao, Y., Broadley, M. R., Dainty, J. R., &amp; &#8230; Hurst, R. (2011). Effects of selenium supplementation on selenoprotein gene expression and response to influenza vaccine challenge: a randomised controlled trial. Plos One, 6(3), e14771. doi:10.1371\/journal.pone.0014771<\/p>\n<p>Hurst, R., Hooper, L., Norat, T., Lau, R., Aune, D., Greenwood, D. C., &amp; Fairweather-Tait, S. J. (2012). Selenium and prostate cancer: systematic review and meta-analysis. The American Journal of Clinical Nutrition, 96(1), 111-122.<\/p>\n<p>Larsen, E. H., Hansen, M., Paulin, H., Moesgaard, S., Reid, M., &amp; Rayman, M. (2004). Speciation and bioavailability of selenium in yeast-based intervention agents used in cancer chemoprevention studies. Journal of AOAC International, 87(1), 225-232. Efficacy of a high-selenium yeast preparation<\/p>\n<p>Li, Y., Dong, Z., Chen, C., Li, B., Gao, Y., Qu, L., &amp; &#8230; Chai, Z. (2012). Organic selenium supplementation increases mercury excretion and decreases oxidative damage in long-term mercury-exposed residents from Wanshan, China. Environmental Science &amp; Technology, 46(20), 11313-11318. doi:10.1021\/es302241v<\/p>\n<p>Lippman, S. M., Klein, E. A., Goodman, P. J., Lucia, M. S., Thompson, I. M., Ford, L. G., &amp; Coltman, C. J. (2009). Effect of selenium and vitamin E on risk of prostate cancer and other cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA, 301(1), 39-51.<\/p>\n<p>Mokhber, N., Namjoo, M., Tara, F., Boskabadi, H., Rayman, M. P., Ghayour-Mobarhan, M., &amp; &#8230; Ferns, G. (2011). Effect of supplementation with selenium on postpartum depression: a randomized double-blind placebo-controlled trial. The Journal of Maternal-Fetal &amp; Neonatal Medicine, 24(1), 104-108. doi:10.3109\/14767058.2010.482598<\/p>\n<p>Rayman, M. P., Searle, E., Kelly, L., Johnsen, S., Bodman-Smith, K., Bath, S. C., &amp; &#8230; Redman, C. G. (2014). Effect of selenium on markers of risk of pre-eclampsia in UK pregnant women: a randomised, controlled pilot trial. The British Journal of Nutrition, 112(1), 99-111. doi:10.1017\/S0007114514000531<\/p>\n<p>Rayman, M. P., Stranges, S., Griffin, B. A., Pastor-Barriuso, R., &amp; Guallar, E. (2011). Effect of supplementation with high-selenium yeast on plasma lipids: a randomized trial. Annals of Internal Medicine, 154(10), 656-665. doi:10.7326\/0003-4819-154-10-201105170-00005<\/p>\n<p>Rayman, M. P., Blundell-Pound, G., Pastor-Barriuso, R., Guallar, E., Steinbrenner, H., Stranges, S., &amp; Guoying, W. (2012). A Randomized Trial of Selenium Supplementation and Risk of Type-2 Diabetes, as Assessed by Plasma Adiponectin. Plos ONE, 7(9), 1-9. doi:10.1371\/journal.pone.0045269<\/p>\n<p>Sindberg, C. D. (2016). Aspects of SelenoPrecise\u00ae documentation: A scientific summary of SelenoPrecise\u00ae absorption, speciation, effects in human material, and bio-marker measurements.\u00a0 Pharma Nord Research Library. Unpublished document.<\/p>\n<p>Tara, F., Rayman, M. P., Boskabadi, H., Ghayour-Mobarhan, M., Sahebkar, A., Alamdari, D. H., &amp; &#8230; Ferns, G. (2010). Prooxidant-antioxidant balance in pregnancy: a randomized double-blind placebo-controlled trial of selenium supplementation. Journal of Perinatal Medicine, 38(5), 473-478. doi:10.1515\/JPM.2010.068<\/p>\n<p>Tara, F., Rayman, M. P., Boskabadi, H., Ghayour-Mobarhan, M., Sahebkar, A., Yazarlu, O., &amp; &#8230; Ferns, G. (2010). Selenium supplementation and premature (pre-labour) rupture of membranes: A randomised double-blind placebo-controlled trial. Journal of Obstetrics &amp; Gynaecology, 30(1), 30-34. doi:10.3109\/01443610903267507<\/p>\n<p>Yu, S. Y., Zhu, Y. J., &amp; Li, W. G. (1997). Protective role of selenium against hepatitis B virus and primary liver cancer in Qidong. Biological Trace Element Research, 56(1), 117-124.<\/p>\n<p>Zachara, B. A., Gromadzinska, J., Palus, J., Zbrog, Z., Swiech, R., Twardowska, E., &amp; Wasowicz, W. (2011). The effect of selenium supplementation in the prevention of DNA damage in white blood cells of hemodialyzed patients: a pilot study. Biological Trace Element Research, 142(3), 274-283. doi:10.1007\/s12011-010-8776-0<\/p>\n<p>The information presented in this review article is not intended as medical advice and should not be used as such.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The evidence from clinical studies shows that high-selenium yeast preparations give the best health outcomes [Alehagen; Blot; Clark; Yu]. Today, I want to look at the documented properties of the high-selenium yeast preparation that was developed for use in the PRECISE studies.\u00a0 PRECISE is the acronym for PREvention of Cancer by Intervention with SElenium.\u00a0 The &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/seleniumfacts.com\/index.php\/documented-properties-high-selenium-yeast-preparation\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Properties of a high-selenium yeast preparation&#8221;<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10,23],"tags":[],"class_list":["post-872","post","type-post","status-publish","format-standard","hentry","category-cancer","category-safety"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Properties of a high-selenium yeast preparation - Seleniumfacts.com<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/seleniumfacts.com\/index.php\/documented-properties-high-selenium-yeast-preparation\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Properties of a high-selenium yeast preparation - Seleniumfacts.com\" \/>\n<meta property=\"og:description\" content=\"The evidence from clinical studies shows that high-selenium yeast preparations give the best health outcomes [Alehagen; Blot; Clark; Yu]. Today, I want to look at the documented properties of the high-selenium yeast preparation that was developed for use in the PRECISE studies.\u00a0 PRECISE is the acronym for PREvention of Cancer by Intervention with SElenium.\u00a0 The &hellip; Continue reading &quot;Properties of a high-selenium yeast preparation&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/seleniumfacts.com\/index.php\/documented-properties-high-selenium-yeast-preparation\" \/>\n<meta property=\"og:site_name\" content=\"Seleniumfacts.com\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/pharmanord7100\" \/>\n<meta property=\"article:published_time\" content=\"2018-02-02T14:46:48+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-02-07T15:25:14+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/seleniumfacts.com\/wp-content\/uploads\/2018\/02\/Se-element-300x80.png\" \/>\n<meta name=\"author\" content=\"Richard Morrill\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Richard Morrill\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"11 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/seleniumfacts.com\\\/index.php\\\/documented-properties-high-selenium-yeast-preparation#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/seleniumfacts.com\\\/index.php\\\/documented-properties-high-selenium-yeast-preparation\"},\"author\":{\"name\":\"Richard Morrill\",\"@id\":\"https:\\\/\\\/seleniumfacts.com\\\/#\\\/schema\\\/person\\\/b9ca24a1c31bad550ee4f8f37996fb0a\"},\"headline\":\"Properties of a high-selenium yeast preparation\",\"datePublished\":\"2018-02-02T14:46:48+00:00\",\"dateModified\":\"2018-02-07T15:25:14+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/seleniumfacts.com\\\/index.php\\\/documented-properties-high-selenium-yeast-preparation\"},\"wordCount\":2155,\"commentCount\":1,\"image\":{\"@id\":\"https:\\\/\\\/seleniumfacts.com\\\/index.php\\\/documented-properties-high-selenium-yeast-preparation#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/seleniumfacts.com\\\/wp-content\\\/uploads\\\/2018\\\/02\\\/Se-element-300x80.png\",\"articleSection\":[\"Cancer\",\"Safety\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/seleniumfacts.com\\\/index.php\\\/documented-properties-high-selenium-yeast-preparation#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/seleniumfacts.com\\\/index.php\\\/documented-properties-high-selenium-yeast-preparation\",\"url\":\"https:\\\/\\\/seleniumfacts.com\\\/index.php\\\/documented-properties-high-selenium-yeast-preparation\",\"name\":\"Properties of a high-selenium yeast preparation - 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