{"id":952,"date":"2018-05-01T07:40:38","date_gmt":"2018-05-01T07:40:38","guid":{"rendered":"http:\/\/seleniumfacts.com\/?p=952"},"modified":"2018-05-01T11:54:02","modified_gmt":"2018-05-01T11:54:02","slug":"selenium-combination-coenzyme-q10","status":"publish","type":"post","link":"https:\/\/seleniumfacts.com\/index.php\/selenium-combination-coenzyme-q10","title":{"rendered":"Selenium in combination with Coenzyme Q10"},"content":{"rendered":"
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Selenocysteine, C3H7NO2Se, is known as the 21st amino acid. It contains selenium as a component. It is a constituent part of the 25 known selenoproteins and selenoenzymes found in the human body. The selenoproteins, in turn, play an important role in the body’s defense against cancer, cardiovascular disease, and neurodegenerative disease.<\/strong><\/figcaption><\/figure>\n

Selenium is an essential micronutrient for us humans.\u00a0 It is a component of the selenoproteins that we need for antioxidant protection and for good immune system function.\u00a0 The selenoproteins glutathione peroxidase, thioredoxin reductase, and selenoprotein P are arguably the most important selenoproteins [Alehagen 2014].<\/strong><\/p>\n

Variability of selenium content and intakes<\/h3>\n

The soil content of selenium and, thus, the dietary intake of selenium varies considerably around the world.\u00a0 Consequently, the need for selenium supplementation differs from region to region of the world.\u00a0 Generally, selenium intakes are lower in Europe than in the United States; there is, however, also considerable variation within the United States.\u00a0 The safest thing to do is to get a plasma or serum selenium concentration test done.<\/p>\n

Minimum daily intakes of selenium<\/h3>\n

Meanwhile, Professor Urban Alehagen, Link\u00f6ping University, Sweden, the lead researcher on the KiSel-10 study<\/a> and a co-researcher on the Q-Symbio study<\/a>, estimates that adults need a minimum daily intake of 75 \u2013 105 micrograms to achieve optimal plasma activity of the selenium containing enzymes glutathione peroxidase and selenoprotein P [Alehagen 2014].\u00a0 Professor Alehagen points out that current estimates are that adults need a daily intake of 75 \u2013 125 micrograms of selenium to achieve reduction of the risk of cancer [Alehagen 2014].<\/p>\n

Optimal form of the selenium supplement<\/h3>\n

In the KiSel-10 study, Professor Alehagen chose to use a pharmaceutical-grade organic high-selenium yeast preparation<\/a> that is made up of numerous selenium species [Alehagen 2014].<\/p>\n

The KiSel-10 study<\/a> was a four-year study of the effect of daily selenium and Coenzyme Q10 supplementation on the heart health of elderly Swedish citizens.\u00a0 The researchers randomly assigned 443 study participants to an active treatment group receiving 200 micrograms of selenium and 200 milligrams of Coenzyme Q10 daily or to a control group receiving matching placebos.<\/p>\n

The data from the KiSel-10 study showed the following significant outcomes of supplementation with selenium and Coenzyme Q10 as compared to the placebo treatment [Alehagen 2013; Johansson 2013]:<\/p>\n