Briefly, the data from the meta-analysis show that selenium decreases the risk of cancer at the highest daily intake levels of the included studies.
This outcome is consistent with the outcomes of a previous study showing a protective effect of selenium at high doses compared to low doses [Cai 2016]. A 2018 meta-analysis used different methods to assess selenium exposure and showed a null association between selenium at high doses compared to low doses [Vinceti 2018].
Adequate intakes of selenium, zinc, and vitamin D are essential to ensure resistance to viral infections, to promote strong immune function, and to reduce levels of inflammation. A team of Norwegian, Swedish, and Russian researchers recommends the initiation of adequate supplementation with these micronutrients in high-risk areas and in cases of suspected exposure to SARS-CoV-2 [Alexander 2020].
The team of researchers concluded from its review of the available medical literature that an adequate selenium intake/status can protect against the hyper-inflammation associated with corona viral infections.
Consequently, individuals at high risk who have a selenium status below 100 micrograms per liter should consider daily supplementation at a dose of 100–200 micrograms of selenium per day [Alexander 2020].
