A meta-analysis shows a significant association between low serum selenium status and rheumatoid arthritis (RA) [Yu 2016].
-The researchers examined the data from 14 case-control studies involving 716 subjects.
-The analysis of the pooled data indicated that patients with rheumatoid arthritis had lower serum levels of selenium than the healthy controls.
-The rheumatoid arthritis patients had significantly lower serum selenium levels than healthy controls did in studies in Europe and in Asia but not in studies in the USA.
Selenium and Rheumatoid Arthritis Studies
Sahebari et al  reported on 13 studies that assessed selenium status in rheumatoid arthritis patients.
- All studies comparing selenium status in rheumatoid arthritis patients and controls showed lower selenium status in the rheumatoid arthritis patients. It is not uncommon that researchers find an association between low selenium intakes/status and increased incidence of autoimmune diseases like rheumatoid arthritis.
- Four of the studies analyzed by Sahebari et al showed an improvement in the clinical symptoms of rheumatoid arthritis patients compared to controls when the patients had been treated with 200-600 micrograms of selenium daily.
Adequate Selenium for Rheumatoid Arthritis Patients
Rheumatoid arthritis is a chronic inflammatory disease that affects the joints of the hands and feet and leads to disability.