Humans with low blood selenium concentrations are more likely to have impaired immune function and rapid mutation of benign variants of RNA viruses to virulent forms. Low blood selenium concentrations are concentrations less than 1 micromol of selenium per liter of blood = less than 78 micrograms of selenium per liter of blood [Harthill].
If a virus-infected, selenium-deficient human host is supplemented with selenium, the mutation rate of the virus tends to decrease, and the immune function tends to improve [Harthill].
significant improvement in Beck Depression Inventory scores, general health questionnaire scores, and depression anxiety and stress scale scores compared with the placebo
significantly reduced total testosterone levels, hirsutism, high-sensitivity C-reactive protein levels (a bio-marker for inflammation), and malondialdehyde levels (a bio-marker for oxidative stress) as well as significantly increased total antioxidant capacity and total glutathione (GSH) levels compared with the placebo
The researchers concluded that the co-administration of probiotics and selenium for 12 weeks to women with PCOS had beneficial health effects.
Selenium: Effect on Metabolic Profile in Patients with PCOS
In a randomized controlled trial enrolling 70 women aged 18 – 40 years, daily supplementation with 200 micrograms of selenium for 8 weeks was associated with the following outcomes compared with placebo [Jamilian 2015]:read more
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