Research conclusion: “The 20% with lowest SELENOP concentrations in a N orth European population without history of cardiovascular disease have markedly increased risk of cardiovascular morbidity and mortality” [Schomburg 2019].
![Low selenoprotein P results in increased risk of heart disease. Heart attack](https://sp-ao.shortpixel.ai/client/to_auto,q_glossy,ret_img,w_300,h_200/https://seleniumfacts.com/wp-content/uploads/2021/10/Heart-disease-300x200.png)
This is the conclusion from the Malmö Preventive Project, a population-based prospective cohort study in southern Sweden, that examined the relationship between plasma selenoprotein P status and 1) risk of all-cause mortality, 2) risk of cardiovascular mortality, and 3) risk of a first cardiovascular event in 4366 study participants.
Note that this was a study done with study participants who had no history of cardiovascular disease. It was truly a study of the relationship between selenium status and the risk of heart disease.