Research done in southern Sweden shows that three blood biomarkers of selenium availability correlated inversely with mortality from breast cancer. The lower the three selenium biomarker levels, the higher the mortality [Demircan 2021].
The blood biomarkers are:
Glutathione peroxidase 3
Breast cancer patients with blood concentrations of these three selenium biomarkers in the highest quintile had significantly better chances of survival compared with patients whose blood levels of these substances were in the lowest quintile [Demircan 2021].
Health benefits of daily supplementation of senior citizens with a combination of selenium and Coenzyme Q10:
improved heart function as shown on echocardiograms
reduced risk of death from heart disease
improved health-related quality of life
The combined supplementation seems to work by reducing the extent of oxidative stress, systemic inflammation, and fibrosis in the study participants [Alehagen 2022a].
Now, data from the KiSel-10 Studyshow the following effects of the combined supplementation with respect to Fibroblast Growth Factor 23 concentrations in blood:
Supplementation decreased concentrations of FGF-23 hormones.
The study showed a relationship between the circulating level of the FGF-23 and atrial fibrillation.
The study showed an association between the concentration of FGF-23 and death from heart disease.
The study showed an effect of reduced FGF-23 levels on the risk of death from heart disease that is independent of the level of the cardiac wall tension bio-marker NT-proBNP.
There exists a close interrelationship between FGF-23 concentrations and kidney function.
Why are FGF-23 Concentrations Important?
Prof. Alehagen explains that FGF-23 is a hormone that is secreted into the blood circulation. One of its primary functions is the regulation of the vitamin D metabolism and of the phosphorous metabolism in the kidneys.
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