Selenium Protects Against Cadmium Poisoning and Atherosclerosis

Cadmium leaking from iron water pipes into drinking water may be a primary cause of increased risk of atherosclerosis – the increased risk of a buildup of plaque on the inside of the artery walls with inflammation as a consequence. This is the thesis of the Danish cardiologist Anton Dorph-Petersen.

Heart attack
Cadmium from drinking water accumulates in the body and causes damage to the layer of cells lining the inside of arteries, leading to a buildup of plaque and to increased risk of atherosclerosis and heart attack. Cadmium is a heavy metal that is found everywhere in the earth. Cadmium accumulates primarily in the liver and kidneys with toxic effects on the kidneys in particular. People with insufficient selenium and iron accumulate more cadmium. Cadmium takes a long time to be eliminated from the body. Iron water pipes and cigarette smoking are significant sources of cadmium in the body.

Dr. Dorph-Petersen asserts that the danger of cadmium toxicity is greatest in regions of the world in which the selenium content of the soil and plants is low and in regions of the world in which there is low dietary intake of selenium containing fish [Dorph-Petersen 2017].

Let me lay out Dr. Dorph-Petersen’s reasoning step by step. His hypothesis has not yet been verified by clinical trials.

However, we do know from a survey of 15,689 study participants in the US that low blood selenium and high blood cadmium are independent risk factors for heart failure. read more

Selenium and Toxic Metals and the Ageing Kidney

In individuals older than 50-60 years, the kidneys’ glomerular filtration rate decreases with increasing age. The glomerular filtration rate is a measure of how well your kidneys are working. In your kidneys, there are tiny filters (called glomeruli) that remove waste and excess fluid from the blood.

Jan Aaseth
Jan Aaseth is a Norwegian physician and professor who has done extensive research in endocrinology, toxicology, and medical biochemistry. Here we summarize his review of the relationship between selenium status, heavy metal toxicity, and the kidneys.

Exposure to toxic metals – mercury, cadmium, lead – can be detrimental to kidneys of normal adults. Accordingly, exposure to toxic metals can affect individuals with reduced glomerular filtration rates even more adversely.

Professor Jan Aaseth and a team of researchers have reviewed the available research data. Their findings show the following relationships [Aaseth 2021]:

Elderly Individuals More Susceptible to Toxic Metal Exposure

Healthy elderly individuals are capable, for the most part, of maintaining normal kidney function. However, especially after the age of 70 years, physiological changes occur in the kidneys. read more