Selenium and Pregnancy

During pregnancy, women need an increased intake of the trace element selenium. Low selenium intake and status in the pregnant mother will be reflected directly in poor selenium status in newborns [Filipowicz 2022].

Newborn children can be low in selenium
There is a strong correlation between the mother’s selenium status during pregnancy and the selenium status of the newborn child.

Women living in regions with low selenium content in the soil and in the food most likely need a selenium supplement. A study conducted in selenium-poor central Poland has revealed that supplemental selenium in a dosage greater than 55 mcg/day can improve pregnant women’s selenium status [Filipowicz 2022].

In the Polish study, one-third of the mothers reported self-initiated additional selenium intake. For the most part, these women took a multi-vitamin and mineral supplement. The tablet added, on average, 42 mcg of selenium to their diets daily. Even so, 79% of these women had serum selenium concentrations below 70 mcg/L (selenium deficiency levels). Moreover, 22% had serum selenium concentrations below 45.9 mcg/L (severe selenium deficiency levels) [Filipowicz 2022]. read more

Selenium Supplementation for Premature Neonates

Preterm neonates are babies born more than three weeks before the normal term, i.e. born before the 37th week of gestation. Sepsis – the condition caused by harmful bacteria entering the blood circulation – is one of the complications associated with premature birth. Selenium supplementation can reduce the risk of late-onset sepsis in preterm neonates.

Selenium supplementation reduces the risk of sepsis in premature babies.

Three studies carried out in low-selenium countries – Australia, New Zealand, and India – have shown a positive effect of selenium supplementation in reducing the incidence of sepsis in premature babies [Daniels; Darlow; Aggarwal].

Selenium supplementation – both selenium fed orally and selenium fed parenterally – significantly improved the selenium status of premature babies and reduced the incidence of “late onset” sepsis [Darlow].

In none of the three clinical studies were there any adverse reactions to the selenium supplementation [Daniels; Darlow; Aggarwal].

Increased Risk of Sepsis in Premature Babies Without Selenium Supplementation

“Late onset” sepsis presents, typically, one week or more following birth and is caused by exposure to infection in the hospital.  A “late onset” sepsis occurs in about one out of five premature babies with a birth weight below 1500 grams (about 3 pounds and five ounces). read more